The clinical significance of sentinel lymph node micrometastasis in breast cancer
نویسندگان
چکیده
منابع مشابه
Sentinel lymph node in cervical cancer
Background: Cervical cancer is the second most common type of cancer among women. Effective screening programs can help cancer detection in early phases and reduce death. Metastasis to lymph nodes is one of the most prognostic factors in patients who underwent surgery. Also, a positive result from pathology report alert oncologist as a cause of death. Sentinel lymph node biopsy has been widely ...
متن کاملSignificance of sentinel lymph node micrometastases in human breast cancer.
BACKGROUND The significance of micrometastatic disease in the sentinel lymph nodes (SLN) of patients with invasive breast cancer has been questioned. The objective of our study was to review the impact of micrometastatic carcinoma detected by SLN biopsy. STUDY DESIGN Between January 1997 and May 2004, 2,408 patients with invasive breast cancer and an SLN with micrometastatic (N0[i+], N1mi) or...
متن کامل2. Significance of Sentinel Node Micrometastasis
Cancer Control 601 The emergence of sentinel lymph node (SLN) biopsy as an alternative method to axillary dissection for staging the axilla in breast cancer patients has brought the value of axillary dissection into close scrutiny. In addition, it has stimulated the assessment of the biologic implications of micrometastatic disease to lymph nodes. Historical review of SLN technology demonstrate...
متن کاملthe accuracy of sentinel lymph node biopsy compared with axillary lymph node dissection in breast cancer
background : sentinel lymph node biopsy is used as an accurate staging procedure to detect early breast cancer. several studies have documented that sentinel lymph node biopsy can accurately determine the status of axillary nodes. sentinel node biopsy offers the advantage of accurately staging the axilla and eliminating the need for a full axillary dissection for patients who have a negative se...
متن کاملNon-sentinel lymph node involvement in patients with breast cancer and sentinel node micrometastasis; too early to abandon axillary clearance.
AIMS It has been suggested that patients with T1-2 breast tumours and sentinel node (SLN) micrometastases, defined as foci of tumour cells smaller than 2 mm, may be spared completion axillary lymph node dissection because of the low incidence of further metastatic disease. To gain insight into the extent of non-sentinel lymph node (n-SLN) involvement, SLNs and complementary axillary clearance s...
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ژورنال
عنوان ژورنال: Breast Cancer Research and Treatment
سال: 2008
ISSN: 0167-6806,1573-7217
DOI: 10.1007/s10549-008-0021-6